Scale choice
Here are some other thoughts...
Many N scale trains just don't start smoothly. Maintenance can be devastatingly critical when it comes to clean track.
Couplers in N scale make the accordian/inchworm effect noticeable, especially if the loco is at all hesitant. I see both of these all the time at shows.
N scale still has that slotcar racer feel about it. It's hard to find a smooth and slow running loco, at least at the shows. I walked alongside one train on a modular setup and could BARELY keep up with it. Figure a marching walk is 3mph which is slower than I was moving, x160 for scale and this thing was putting the TGV to shame. This was larger steamer too. Looked nice pulling all those cars, but silly. It's not really a point against the scale itself since it's your layout and you can obviously deal with that, but it does point to the way the locos are designed and built. Sane scale speeds may not be readily possible for what you want to run.
Eyesight and such begins to factor in. What may be fine now may not be so great in a few years when you struggle to see what your doing or require a small sun over your shoulder to see the details. It's already a factor with my wife who just wants to WATCH the trains, but not necessarily be involved. N scale would be pointless for her. As it is, HO may be pointless for her in a few years, but she can at least see the some of the details now.
Sound may or may not be a factor. Given what can be put in N scale you may automatically get scale sound simply because you can't get the volume you would in a larger scale. This is probably a plus for a room full of N engines since you won't be able to blast yourself out of the room even if you wanted to. All bets are off if you install speakers under the layout though.
Kids/grandkids are often less than gentle, but with the general lack of details in N scale this might actually be a point in favor of N vs. HO. OTOH, it's probably less likely that the HO locomotive will end up on the floor with the other toy cars playing smashemup, at least not without you noticing.
Effects. Lighting is getting better all the time. I've got a nice B23-7 for Conrail that has independant lighting of front/rear red markers, and # boards. This isn't to say you couldn't do this in N scale. I'm sure you could, but it would be much harder to do. I like having all the extra lighting options and I'd be struggling to do what I have done in the past in N scale. OTOH, I've heard of someone who used a plc and managed to do a rotary beacon in N scale using 6 SMT LEDs. Kudos to him, but it's just not something I'd have the ability to do.
The biggest one I'm struggling with is eyesight and dexterity. I was at the nationals this year and at the NCE booth I watched some of the late teens help try and deal with an N scale loco. It took forever for them to get it on the tracks and then we all discovered the wheelset was damaged and whatnot. Just figuring all that out too forever since no one could actually see what was going on. That pretty much staked any consideration of smaller scales right then and there, not that those thoughts were common but still. I don't want to think about whether or not I can do this when I hit my 40s, let alone a couple decades past that. My wife already has a hand tremor so many times she can't help me put anything on the track or move stuff around easily. It's also another reason I've canned the idea of putting in ground throws. Stuff like that will be fascia mounted. I'm still going with Sergent couplers though. For me N scale would just be a waste of time/effort/money. YMMV.
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